Determination of Chromium, Selenium, and Molybdenum in Nutritional Products by ICP-MS Authors
نویسندگان
چکیده
An ICP-MS validated method for the rapid determination of chromium (Cr), selenium (Se), and molybdenum (Mo) in infant formula and adult nutritional products was successfully transferred from the Agilent 7500cx ICP-MS to the Agilent 7700x ICP-MS, and from lab 1 to lab 2, respectively. The key advantage of the method is that all samples can be analyzed using a single-cell gas mode (helium mode) that provides effective removal of polyatomic interferences on Cr, Mo, and Se. This results in significantly improved productivity. Samples were spiked with internal standards before digestion in a closed-vessel microwave oven, followed by detection using ICP-MS. This method was found to be a suitable candidate for use as a global reference method, and has been granted Final Action/Official status by AOAC for the determination of Cr, Mo, and Se at trace levels in nutritional products.
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